Título

OPHTHALMOLOGICAL STRUCTURAL AND FUNCTIONAL FEATURES IN INFANTS WITH MICROCEPHALY RELATED TO PRESUMED CONGENITAL ZIKA SYNDROME IN CEARA, BRASIL.

Objetivo

Purpose: To describe and analyze ophthalmological features in children with microcephaly due to presumed congenital Zika syndrome (CZS). Settings: This study was conducted in a non-governmental organization (NGO) clinic for visually disabled children in Fortaleza, Ceara State.

Método

Methods: Ophthalmological evaluation, eye fundus observation and imaging, visual acuity test with Teller acuity cards and ocular motility evaluation were performed, from January to May 2016.

Resultado

Results: Seventy infants with microcephaly were referred to the NGO clinic. Twenty-five patients presented ophthalmological abnormalities. The average age was three months. Eighteen patients (26%) among the group of 70 children with microcephaly due to presumed CZS presented with intraocular abnormalities including macular chorioretinal atrophy, mottled retinal pigment epithelium and optic nerve pallor. Seven patients (10%) presented early onset strabismus or nystagmus without intraocular lesions.

Conclusão

Conclusion: Ophthalmological abnormalities occurred in 36% of the patients. Circumscribed atrophic chorioretinal lesions, macular abnormalities, focal mottling of retinal pigments, optic nerve abnormalities, low visual acuity, strabismus and nystagmus were common ophthalmological features in patients with microcephaly due to presumed CZS.